Mutant Plague

9th-level transmutation (sorcerer, wizard)

Casting Time: 1 action

Range: 60 feet

Components: V, S, M (a vial of blood from two mana-wasted mutants of different creature types)

Duration: instantaneous

Choose a number of creatures equal to your level that you can see within range. All targets that fail a Constitution saving throw are instantly infected with mana fever, and they become highly infectious carriers of a deadly mutagenic plague. As long as a carrier has its Charisma reduced by at least 1, they remain unaware of their illness. If their Charisma restored without curing their disease, they become aware of their condition. A carrier’s disease is difficult to remove, requiring an ability check (1d20 + spellcasting ability modifier) against your spell save DC + 3.

Disease: Mana fever. A creature makes an initial Constitution saving throw (as above) and any subsequent saving throws are at your spell save DC + 3. At the end of its next long rest, a creature with this disease makes its saving throw or lowers its Constitution score by 1d3 and its Charisma score by 1d3. A creature naturally fights off this disease by making 2 consecutive successful saving throws to resist it.

As long as a carrier is infected by the disease from this spell, it can spread the mutant plague to any creature it damages with its natural weapons. Each round a target takes damage from a carrier’s natural weapons (regardless of how many natural weapons hit), that target must making a Constitution saving throw or become infected with the common version of mana fever, which is less virulent than the original strain imparted by the mutagenic meltdown and can be cured as any other supernatural disease. At the GM’s discretion, creatures that share food or drink or have sexual contact with the carrier must also save or contract mana fever.

Mana fever is a supernatural disease and cannot be healed or cured without the aid of magic. Anyone who lives with mana fever for a week straight without dying becomes immune to the disease, but also becomes a mana-wasted mutant.